The cross sectional view of a vessel showing thrombotic thrombocytopenic purpura (TTP) antibodies binding with ADAMTS13 protease molecules, preventing the Von Willebrand factor strands to be cut into smaller pieces. When this occurs, the Von Willebrand factor strands become powerful aggregators of platelets and entrap red blood cells, forming a much larger than normal thrombus and eventually blocking blood flow in the vessel.
